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 rubinov and sporn 2010


Overview of Graph Theory and Alzheimer's Disease

#artificialintelligence

The Roman physician Galen was among the first people to realize that the brain controlled motor responses, cognitive function, and memory. Ever since Galen, this question has propelled the field of neuroscience. Beginning with Paul Broca's work in the 1800s, brain function has been described in terms of modular separation: each region in the brain controls a unique set of behaviors, actions, and capacities. This determination was made through observation of patients suffering neurological symptoms and connecting them to localized brain injuries. For example, Broca's area (a brain region in the inferior frontal gyrus) was found to be responsible for speech fluency (Acharya and Wroten 2022), and was discovered by studying two subjects, both of whom exhibited reduced speech capacity and suffered from lesions in the same area of the brain.